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KMID : 1132720110090030136
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Genomics & Informatics
2011 Volume.9 No. 3 p.136 ~ p.137
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A Visualization Tool for Computational Analysis of DNA Methylation Level Using Bisulfite Sequencing Data
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Tae Hong-Seok
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Abstract
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Methylation of cytosine is a post-synthesis modification that does not affect the primary DNA sequence but greatly influences gene expression level and phenotypes of an organism. As high-throughput sequencing of bisulfite-treated DNA is the most efficient method to identify methylated sites, several tools to map sequencing reads on a reference are available. But tools to visualize and to interpret the methylation level of methylation sites are currently insufficient. Herein, we present a novel tool to visualize the methylation level of CpG sites.
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KEYWORD
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visualization, DNA methylation, bisulfite sequencing, epigenetics, MethylDraw
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